The drone-based aerial platform offers various applications such as security and emergency response, delivery, defense, inspection, mapping, film, and entertainment. For safe driving, an automated vehicular navigation system (AVNS) must have a precise location. Although the vehicle location can be retrieved in GPS-friendly surroundings, the positioning accuracy of AVNS is easily reduced in GPS-denied environments (such as suburbs, tunnels, forests, and indoor scenarios). Researchers have already developed various methods to handle UAV navigation in GPS-less environments, such as Visual Odometry (VO) and Simultaneous Localization and Mapping (SLAM). This paper proposes a new Qualcomm Snapdragon referenced visual-inertial odometry (VIO) algorithm for indoor GPS-denied Micro Aerial Vehicle (MAV) navigation. The custom-built MAV is comprised of a hardware platform equipped with a VOXL flight companion computer, PX4 flight controller, pre-calibrated stereo and tracking sensors, a high