Hydrogen combustion in internal combustion engines offers numerous advantages, such as zero CO2 emissions and high flame speed, which make it a promising alternative fuel for green vehicle solutions. In order to maximize the engine performance with hydrogen, however, meticulous calibration of the air-fuel mixture must be performed, particularly when lean and stoichiometric combustion conditions are considered. Lean burning, i.e., excess air, offers better thermal efficiency and lower NOx emissions but can cause lower engine power and combustion instability. Stoichiometric combustion, however, ensures a complete fuel-air mixture but at the cost of higher combustion temperature and high NOx emissions. Calibration strategies for hydrogen engines are presented in this paper by comparing the lean and stoichiometric strategies and their implications on engine power output, efficiency, and emissions. Test data from several hydrogen engine configurations demonstrate that lean burn with EGR