Under high-speed working conditions of an engine, the lubrication and tribological performance (LTP) of the crankpin bearing (CB) are strongly influenced by the oil film pressure (p) and asperity contact in the mixed lubrication regime (MLR) of CB, while these parameters mainly depend on the CB’s geometrical dimensions including the bearing radius (r b), bearing width (B), surface roughness (σ), gap between crankpin and bearing (c), and crankpin speed (ω). To analyze the sensitivity of the dynamic parameters of the r b, B, σ, c, and ω on the CB’s LTP, a hybrid model of the piston-rod-crank dynamic and CB lubrication is proposed to establish the dynamic equations of the CB. An algorithm program written in MATLAB software is then applied to solve the dynamic equations. The effect of the dynamic parameters of the r b, B, σ, c, and ω on the CB’s LTP is simulated and evaluated via the indexes of the p, asperity contact force, friction force, and friction coefficient. The research results