Browse Topic: Diseases

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Paper-Based Technology Advances Earlier Cancer DetectionTBMG-373458/1/2020
Washington State University researchers have developed a technology that is more than 30 times more sensitive than current lab-based tests in finding early stage cancer biomarkers in blood.
Powering Up Medtech’s Modalities: Top Trends and Design ConsiderationsTBMG-373508/1/2020
We are living in a digitally integrated and connected world. Evidenced by the use of smartphones, smartwatches, and other smart devices, there is no ending this trend. This holds true across many industries and applications, but is especially prevalent within medtech devices — a market that’s predicted to reach $432.6 billion by 2025.1
Wearable Patch May Provide New Treatment Option for Skin CancerTBMG-373538/1/2020
Conventional melanoma therapies, including chemotherapy and radiotherapy, suffer from the toxicity and side effects of repeated treatments due to the aggressive and recurrent nature of melanoma cells.
Tiny, Magnetically Powered Implant Stimulates Brain Without BatteryTBMG-373448/1/2020
Rice University neuroengineers have created a tiny surgical implant that can electrically stimulate the brain and nervous system without using a battery or wired power supply.
Leading Women in Engineering & Science: Tracy Campbell Accardi, Vice President, Surgical Robotics Research & Development, MedtronicTBMG-362903/1/2020
What led you to choose science and/or engineering as a career, particularly in the medical device industry?
Wireless System Powers Devices Inside the BodyTBMG-361693/1/2020
In the brain, implantable electrodes that deliver an electrical current are used for a technique known as deep brain stimulation, which is often used to treat Parkinson’s disease or epilepsy. These electrodes are now controlled by a pacemaker-like device implanted under the skin, which could be eliminated if wireless power is used. Wireless brain implants could also help deliver light to stimulate or inhibit neuron activity through optogenetics, which so far has not been adapted for use in humans but could be useful for treating many neurological disorders.
Researchers Hope to Make Needle Pricks for Diabetics a Thing of the PastTBMG-362403/1/2020
Patients with diabetes have to test their blood sugar levels several times a day to make sure they are not getting too high or too low. Studies have shown that more than half of patients don’t test often enough, in part because of the pain and inconvenience of the needle prick.
Tiny Magnetics Show Promise for Medical ApplicationsTBMG-362463/1/2020
Small magnetic objects are showing promise in the biomedical field. Magnetic nanostructures have interesting properties that enhance novel applications in medical diagnosis and allow the exploration of new therapeutic techniques.
AI-Analyzed Blood Test Predicts Disease ProgressionTBMG-362523/1/2020
Scientists used an AI algorithm to analyze the blood and post-mortem brain samples of 1,969 patients with Alzheimer’s and Huntington’s disease. Their goal was to find molecular patterns specific to these diseases.
Machine Keeps Human Livers Alive for One Week Outside of the BodyTBMG-362573/1/2020
Until now, livers could be stored safely outside the body for only a few hours. With the novel perfusion technology, livers — and even injured livers — can now be kept alive outside of the body for an entire week. This is a major breakthrough in transplantation medicine, which may increase the number of available organs for transplantation and save many lives of patients suffering from severe liver disease or a variety of cancers.
Engineers Design Bionic ‘Heart’ for Testing Prosthetic Valves, Other Cardiac DevicesTBMG-362623/1/2020
As the geriatric population is expected to balloon in the coming decade, so too will rates of heart disease in the United States. The demand for prosthetic heart valves and other cardiac devices — a market that is valued at more than $5 billion dollars today — is predicted to rise by almost 13 percent in the next six years.
Discovery Takes Pressure Off Blood MeasurementsTBMG-362643/1/2020
Researchers at Monash University are on the verge of creating a revolutionary, portable blood pressure monitoring device that can provide data continuously to patients from the comfort of their home.
Leading Women in Engineering & Science: Making their Mark in Medical HistoryTBMG-362703/1/2020
While women are still underrepresented in STEM fields, including the medical device industry, those who have chosen science and engineering as a profession are making a huge impact. The women in this industry are passionate about bringing solutions to the market that improve patient outcomes and transform patient’s lives. They have broken through barriers to go on to develop transformational devices, fight diseases, and create revolutionary materials. This feature presents insights from a handful of these women, including industry leaders, inventors, entrepreneurs, and those inspiring other women through education.
Embedded Computer Computer Vision in Medical Technology: Focus on Mobile and eHealth DevicesTBMG-362683/1/2020
Color video technology paired with artificial intelligence holds great development potential for the future optimization of patient care. Mobile systems have an important role to play in this context, and OEMs need solutions that integrate embedded vision and embedded computer technology.
Portable Device Helps Doctors Diagnose Sepsis FasterTBMG-362673/1/2020
EPFL Lausanne, Switzerland
Self-Moisturizing, Smart Contact LensesTBMG-361583/1/2020
Researchers have developed a new type of self-moisturizing, smart contact lenses that maintain a layer of fluid between the contact lens and the eye using a novel mechanism.
Cold Plasma Patch Could Make Immunotherapy More Effective for Treating MelanomaTBMG-362373/1/2020
An interdisciplinary team of researchers at the UCLA Jonsson Comprehensive Cancer Center has developed a medicated patch that can deliver immune checkpoint inhibitors and cold plasma directly to tumors to help boost the immune response and kill cancer cells.
Iron Nanorobots Destroy Cancer CellsTBMG-362383/1/2020
Drug-coated iron nanowires that can be guided to the site of a tumor using an external magnetic field before activating a three-step cancer-killing mechanism could provide an effective option for cancer therapy.
Leading Women in Engineering & Science: Robyn Meurant, Executive Director, Regulatory Services, IVDs and Medical Devices, NSF InternationalTBMG-363093/1/2020
What led you to choose science and/or engineering as a career, particularly in the medical device industry?
Blood Test Detects Multiple Types of CancerTBMG-361763/1/2020
A new blood test uses next-generation sequencing technology to probe DNA for tiny chemical tags (methylation) that influence whether genes are active or inactive. When applied to nearly 3,600 blood samples — some from patients with cancer and some from people who had not been diagnosed with cancer at the time of the blood draw — the test successfully picked up a cancer signal from the cancer patient samples and correctly identified the tissue from where the cancer began (the tissue of origin). The test’s specificity — its ability to return a positive result only when cancer is actually present — was high, as was its ability to pinpoint the organ or tissue of origin.
Remote, Noninvasive Cardiac Activity Tracer (RENCAT)TBMG-361773/1/2020
NASA Langley Research Center has developed a novel laser vibrometer sensor for monitoring cardiac activities remotely and non-invasively — specifically, heart functions of valve/chamber opening and closing cycles (cardiac cycles). The device provides precise magnitude and timing information, non-invasively and away from the heart region without interference by patient garments.
Smart Photonic Contact Lens for Diabetic Diagnosis and Retinopathy TreatmentTBMG-360222/1/2020
Diabetic patients need to measure their blood sugar level by drawing blood before and after a meal. It is easy to develop complications due to diabetes. Recently, a research team from Pohang University of Science and Technology (POSTECH) developed technology that allows diagnosis of diabetes and treatment of diabetic retinopathy just by wearing smart light-emitting diode (LED) contact lens. With this technology, it the researchers hope to develop wearable diagnostic and therapeutic devices for diabetes.
Artificial Neurons Cure Chronic DiseasesTBMG-360182/1/2020
Artificial neurons on silicon chips that behave just like the real thing have been invented by scientists — a first-of-its-kind achievement with enormous scope for medical devices to cure chronic diseases, such as heart failure, Alzheimer’s, and other diseases of neuronal degeneration.
Liquid-Metal Wearable Pressure Sensor Created for Health Monitoring ApplicationsTBMG-360092/1/2020
KAIST Daejeon, Republic of Korea
Bone Bandage Soaks Up Pro-Healing Biochemical to Accelerate RepairTBMG-360162/1/2020
Researchers at Duke University have engineered a bandage that captures and holds a pro-healing molecule at the site of a bone break to accelerate and improve the natural healing process. In a proof-of-principle study with mice, the bandage helped to accelerate callus formation and vascularization to achieve better bone repair by three weeks.
AI Identifies Previously Unknown Cancer FeaturesTBMG-360232/1/2020
Artificial intelligence (AI) technology has successfully found features in pathology images from human cancer patients, without annotation, that could be understood by human doctors. Further, the AI identified features relevant to cancer prognosis that were not previously noted by pathologists, leading to a higher accuracy of prostate cancer recurrence compared to pathologist-based diagnosis. Combining the predictions made by the AI with predictions by human pathologists led to an even greater accuracy.
Diagnosing Prostate Cancer with Artificial IntelligenceTBMG-360212/1/2020
Researchers at Radboud UMC have developed a “deep learning” system that is better than most pathologists at determining the aggressiveness of prostate cancer. The AI system, which uses tissue samples to arrive at its diagnosis, taught itself to identify prostate cancer based on data from over 1200 patients. The Radboud team is now working with researchers from the Karolinska Institute in Sweden and Kaggle, a Google subsidiary, with the intention to continue developing these methods as part of a major international competition.
Micro Device Detects Ebola Virus Using Bio-SensorsTBMG-358011/1/2020
A prototype micro device with biosensors was developed that can detect the deadly Ebola virus. With this type of device, those infected can be treated earlier, and the early detection process can potentially decrease the spread of infections.
Making a Great Cardio Product Even Better: The Next-Generation Zio Heart PatchTBMG-357791/1/2020
Nearly half of all adults in the United States have some type of cardiovascular disease. This group of over 121 million people are often diagnosed with potential arrhythmias but physicians need to be able to diagnose them quickly and efficiently to ultimately save lives. One company is redefining the way cardiac arrhythmias are clinically diagnosed to help physicians do just that. The new device from iRhythm “combines wearable biosensor devices worn for up to 14 days and cloud-based data analytics with powerful proprietary algorithms that distill data from millions of heartbeats into clinically actionable information,” the company says.
AI Blood Test Spot Signs of Brain TumorsTBMG-357681/1/2020
Researchers have developed a test that works by detecting chemical clues shed by brain tumors into the blood. They say it could help improve brain tumor survival by making diagnosis quicker and more efficient.
Wirelessly Controlled Ingestible CapsuleTBMG-357891/1/2020
Researchers have developed an ingestible capsule that can be controlled using Bluetooth wireless technology. The capsule — which can be customized to deliver drugs, sense environmental conditions, or both — can reside in the stomach for at least a month, transmitting information and responding to instructions from a user's smartphone.
Low-Field MRI Improves Lung, Cardiac ImagingTBMG-357731/1/2020
National Institutes of Health researchers, along with researchers at Siemens, have developed a high-performance, low-magnetic-field MRI system that vastly improves image quality of the lungs and other internal structures of the human body. The new system is more compatible with interventional devices that could greatly enhance image-guided procedures that diagnose and treat disease, and the system makes medical imaging more affordable and accessible for patients.
Method Speeds 3D Printing of Millimeter-Sized Imaging LensesTBMG-3571512/1/2019
A new method was developed to make a low-cost, high-quality lens quickly using a 3D printer. The technology could be used to create optical imaging lenses, customized contact lenses for correcting distorted vision, or to turn iPhones into microscopes for disease diagnosis.
Microneedle Biosensors Accurately Detect Patient Antibiotic Levels in Real TimeTBMG-3562112/1/2019
Small, non-invasive patches worn on the skin can accurately detect the levels of medication in a patient’s system, matching the accuracy of current clinical methods. In a small-scale clinical evaluation, researchers at Imperial College London have shown for the first time how microneedle biosensors can be used to monitor the changing concentration of antibiotics.
Implantable Cancer Traps Could Provide Earlier Diagnosis, Help Monitor TreatmentTBMG-3562812/1/2019
Invasive procedures to biopsy tissue from cancer-tainted organs could be replaced by simply taking samples from a tiny “decoy” implanted just beneath the skin, University of Michigan researchers have demonstrated in mice.
Prototype Smartphone App Can Help Parents Detect Early Signs of Eye Disorders in ChildrenTBMG-3562212/1/2019
A Baylor University researcher’s prototype smartphone app — designed to help parents detect early signs of various eye diseases in their children such as retinoblastoma, an aggressive pediatric eye cancer — has passed its first big test.
Novel Applications of Electrospinning Could Improve DevicesTBMG-3563612/1/2019
When you visit Andrew Steckl’s lab at the University of Cincinnati, you see a nondescript glass box that weaves together different fibers. He sees endless possibility.
Camera Enables Surgeons to More Easily Identify Cancerous TissueTBMG-3542911/1/2019
Many surgeons rely on sight and touch to find cancerous tissue during surgery. Large hospitals or cancer treatment centers may also use experimental near-infrared fluorescent agents that bind to tumors so surgeons can see them on specialized displays. These machines are costly, making them difficult for smaller hospitals to procure. They also are very large, making them difficult to fit into an operating suite and integrate smoothly into surgery, and they require the lights to be dimmed so the instruments can pick up the weak fluorescent signal, making it difficult for the surgeons to see.
2019 'Create the Future' Medical Category Winner: Cervical Stabilization DeviceTBMG-3551511/1/2019
Miniaturizing Medical Imaging, Sensing TechnologyTBMG-3550111/1/2019
Scientists have used a microchip to map the back of the eye for disease diagnosis. This is the first time that technical obstacles have been overcome to fabricate a miniature device able to capture high-quality images.
5 Ws of the E-Tattoo for Heart MonitoringTBMG-3543411/1/2019
Anyone suffering from heart disease or other heart ailments that require regular heart monitoring. The new wearable technology could make heart health monitoring easier and more accurate than existing electrocardiograph machines — a technology that has changed little in almost a century.
Scientists Create Pancreas on a ChipTBMG-3549711/1/2019
By combining two powerful technologies, scientists are taking diabetes research to a whole new level. In a study led by Harvard University’s Kevin Kit Parker and published in the journal Lab on a Chip, microfluidics and human, insulin-producing beta cells have been integrated in an islet-on-a-chip. The new device makes it easier for scientists to screen insulin-producing cells before transplanting them into a patient, test insulin-stimulating compounds, and study the fundamental biology of diabetes.
Electronic Nose Can Sniff Out Which Lung Cancer Patients Will Respond to ImmunotherapyTBMG-3549511/1/2019
European Society for Medical Oncology Lugano, Switzerland
2019 Create the Future Design Contest Grand Prize Winner: ULiSSESTBMG-3550711/1/2019
Microfluidics Device Helps Diagnose SepsisTBMG-3534510/1/2019
A novel sensor could dramatically accelerate the process of diagnosing sepsis, a leading cause of death in U.S. hospitals that kills nearly 250,000 patients annually. To diagnose sepsis, doctors traditionally rely on various diagnostic tools, including vital signs, blood tests, and other imaging and lab tests.
New Optical Endoscopy Using Ultrasound Could Replace ScopesTBMG-351019/1/2019
One day, scopes may no longer need to be inserted into the body — such as down the throat or under the skin — to reach the stomach, brain, or any other organs for examination.
Microrobots Activated by Laser Pulses for Treating TumorsTBMG-351539/1/2019
Microrobots that can deliver drugs to specific spots inside the body while being monitored and controlled from outside the body have been developed that also can treat tumors in the digestive tract.
3D Printed Pill Samples Gut Microbiome to Aid Diagnosis and TreatmentTBMG-350889/1/2019
A research team led by Tufts University engineers has developed a 3D printed pill that samples bacteria found in the gut — known as the microbiome — as it passes through the gastrointestinal tract (GI). The ability to profile bacterial species inhabiting the gut could have important implications for the diagnosis and treatment of conditions that are affected by the microbiome, according to the researchers.
Senior Virtual Assistant Mitigates Impact of Dementia and DeliriumTBMG-350909/1/2019
An estimated 50 million people worldwide are living with dementia, resulting in more than $1 trillion each year in healthcare costs. Artificial emotional intelligence (AEI) technology developer BPU Holdings has been researching methods to reduce the complications associated with the disease. Its senior virtual assistant (SeVA) technology utilizes computer-simulated emotion to provide a new level of support for dementia patients to mitigate their pain. In doing so, the technology is expected to reduce treatment costs in the millions of dollars globally.
Pen and Autoinjectors: Testing for the FutureTBMG-350829/1/2019
The injectable drug-delivery device market is growing at a staggering rate, with an anticipated global market value of $37.5 billion by 2025 compared to $16.7 billion in 2016. The driving factors of this growth are the increasing geriatric population and the rising incidence rates of chronic and autoimmune diseases such as diabetes and multiple sclerosis. Allergies causing anaphylactic reactions are also increasing dramatically, particularly in industrially developed countries.
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